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Perform DEqMS

Usage

perform_DEqMS(
  fit,
  se,
  DEqMS_PSMs_column = NULL,
  logFC = TRUE,
  logFC_up = 1,
  logFC_down = -1,
  p_adj = TRUE,
  alpha = 0.05
)

Arguments

fit

eBayes object resulting from perform_limma method

se

SummarizedExperiment containing all necessary information of the proteomics data set

DEqMS_PSMs_column

String specifying which column name to use for DEqMS (default NULL). Any column of the rowData(se) is accepted.

logFC

Boolean specifying whether to apply a logFC threshold (TRUE) or not (FALSE)

logFC_up

Upper log2 fold change threshold (dividing into up regulated)

logFC_down

Lower log2 fold change threshold (dividing into down regulated)

p_adj

Boolean specifying whether to apply a threshold on adjusted p-values (TRUE) or on raw p-values (FALSE)

alpha

Threshold for adjusted p-values or p-values

Value

data.table of DE results